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Sustained Release Drug Delivery System: A Review

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Introduction: Presently pharmaceutical industries are focusing on development of sustained release formulations due to its inherent boons. Sustained release dosage forms are designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time. The basic rationale of sustained release drug delivery system optimizes the biopharmaceutical, pharmacokinetic and pharmacodynamics properties of a drug in such a way that its utility is maximized, side-effects are reduced and cure of the disease is achieved. Sustained release (SR) preparations are not new but several new modifications are being introduced. Rising number of patent expirations and soaring need for pediatric and geriatric dosage forms are providing a boost to the growth of the market. Growing awareness regarding added benefits provided by sustained release formulations is also stimulating the growth of the market.   SR has received most of the attention because of the fact that the