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Showing posts from June, 2021

Encapsulated tablet system: Future Requirements

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  Solid oral dosage forms are most acceptable dosage forms especially tablets are most widely accepted by people of different age groups. A multifunctional and multiple unit system for oral use are developed by filling versatile mini tablets in a capsule. It is a multifunctional and multiple unit system for oral use and can be developed by filling versatile tablets in a capsule, for example: Immediate release mini tablets, Rapid-release Mini-Tablets (RMTs), Sustained release Mini-Tablets (SMTs), Pulsatile Mini-Tablets (PMTs), and Delayed-onset Sustained release Mini-Tablets (DSMTs). In this technology we can reduce the size of the tablet such that it could be enclosed in a capsule, and then deployed within one single dosage form. Mini tablets are multiple unit dosage forms and are advantageous than pellets or any other oral dosage forms as they are easy to manufacture, and stability problems are less. The oral controlled release drug delivery system included two types of dosage for...

Medicated Chewing Gum (MCG): A Novel Oral Drug Delivery System

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  Medicated chewing gums (MCG) have a wide range of applications in health care, including drug delivery and neutraceuticals. These gums are used for the prevention and treatment of motion sickness and dental caries and smoking for cessation. The popularity of medicated chewing gums as drug delivery systems is increasing due to their advantages such as non-invasiveness, easy administration, and faster metabolism through the liver or gut wall. Moreover, the trend of using biodegradable chewing gums is increasing due to a ban on synthetic polymer-based chewing gums in Singapore and other parts of the world.    Drugs released while chewing can either be absorbed directly into the bloodstream via the buccal membrane or it could be swallowed with saliva and absorbed in the gastrointestinal (GI) tract. As most of the given drug in MCGs gets absorbed, a reduced dose may be required, lowering the chances of side effects. The drug concentration that is absorbed via the GI tract is...